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Insights / Deals & Transactions
February 16, 2026/9 min read/Updated October 19, 2026

Pharma Deals Database 2026: Major Licensing and M&A Deals, Verified

116 of 2026’s major biopharma licensing deals and acquisitions in one searchable table, each checked against its source. Filter by type, month, therapeutic area or company, and download the data as CSV.

Pharma Deals Database 2026: Major Licensing and M&A Deals, Verified
Fig. 01 / Deals & Transactions / February 16, 2026Source: VLS Research

The 2026 Deals Database

This database brings together our two verified 2026 deal logs: licensing deals with a disclosed total of $1 billion or more or an upfront of $100 million or more, and acquisitions of drug companies worth $1 billion or more. Every entry was checked against the company announcement or a primary report, which the table links to. Verified through 19 October 2026.

Showing 116 of 116 deals. The CSV contains the deals shown.

DateDealType and areaValue
19 OctRoche ← Hansoh PharmaPortfolio of antibody–drug conjugate programsLicensingOncologyChina-originOver $15BUpfront: $400M (+$110M at year one)
19 OctMerck KGaA → Silence TherapeuticssiRNA medicines for rare and specialty diseasesM&ARare disease~$1.3B equity value ($1.1B EV)$20.00/ADS cash; premium 130% to prior close
15 OctAstraZeneca ← insitroAI-enabled discovery in MASH and cardiomyopathiesLicensingObesity & metabolicUp to ~$1.5BUpfront: $40M
14 OctGilead ← Vir BiotechnologyThree dual-masked T-cell engagers for solid tumorsLicensingOncologyUp to ~$1.9BUpfront: $90M (cash + equity)
13 OctRoche ← Rona TherapeuticsALK7-targeting RNAi for obesityLicensingObesity & metabolicChina-originUp to ~$1.16BUpfront: Up to $100M upfront & near-term
8 OctViatris → Pacira BioSciencesNon-opioid pain therapiesM&ASpecialty & generics~$1.65B$36.50/share cash
5 OctShionogi → IntraBioRare neurodegenerative disease franchiseM&ARare disease~$2.0BUpfront cash
5 OctCSL ← Alentis TherapeuticsLixudebart, anti-claudin-1 antibody for kidney and liver diseaseLicensingCardiovascular & renalUp to ~$1.56BUpfront: $355M
5 OctGenentech (Roche) ← AlectorAL050, brain-penetrant GCase enzyme replacementLicensingNeuroscienceUp to ~$1.27BUpfront: $100M
2 OctNovartis ← AbogenABO2203, mRNA-encoded CD19×CD3 T-cell engager + optionsLicensingImmunologyChina-originUp to ~$7.8BUpfront: $575M
1 OctSanofi ← RegeneronFour long-acting antibodies incl. REGN20423 (IL-13) — 50:50 profit shareLicensingImmunologyUp to ~$8BUpfront: $1.0B
29 SepNovo Nordisk ← Jiangsu HengruiHRS-1596, oral GLP-1/GIP dual agonistLicensingObesity & metabolicChina-originUp to $2.6BUpfront: $300M
28 SepMerck & Co. ← SciBrunch TherapeuticsSPR2015, oral KRAS G12D (ON) inhibitorLicensingOncologyChina-originUp to $2.13BUpfront: $400M
24 SepEli Lilly ← InnoCare PharmaDiscovery programs against up to five targetsLicensingPlatform / multi-areaChina-originUp to ~$3.35BUpfront: Up to $100M upfront & near-term
24 SepRoche ← Atavistik BioAllosteric small molecules for cardiometabolic diseaseLicensingObesity & metabolicUp to ~$1.97BUpfront: $70M
24 SepGenentech (Roche) ← Earendil LabsOncology bispecific antibodiesLicensingOncologyOver $1.5BUpfront: $55M
22 SepBoehringer Ingelheim ← EnvisagenicsRNA-splicing-derived oncology targetsLicensingOncologyOver $1.0BUpfront: Undisclosed
21 SepTelix Pharmaceuticals → ITM Isotope Technologies MunichITM-11 radioligand therapyM&ARadiopharmaceuticalsUp to $2.35B$1.65B upfront (mostly Telix shares) + up to $700M milestones
17 SepNovo Nordisk ← Orbis MedicinesOral macrocycles for cardiometabolic diseaseLicensingObesity & metabolicUp to $1.4BUpfront: Undisclosed
17 SepRoche ← Dualitas TherapeuticsBispecific antibodies for immunologyLicensingImmunologyUp to $1.0BUpfront: $36.5M
3 SepGSK ← HUTCHMEDHMPL-A830, KRAS-EGFR antibody-targeted therapy conjugateLicensingOncologyChina-originUp to $1.295BUpfront: $110M
3 SepMedicus Pharma ← PfizerPF-08046031, ADC discontinued by PfizerLicensingOncologyOver $1.0BUpfront: $12M (+$15M at year one)
2 SepNovartis ← AlteogenALT-B4 hyaluronidase for subcutaneous products — option & licenseLicensingPlatform / multi-areaUp to ~$3.22BUpfront: Undisclosed
1 SepRoche ← Simcere ZaimingSIM0660, CD79a/CD19/CD3 trispecific T-cell engager for B-cell malignanciesLicensingOncologyChina-originUp to $1.53BUpfront: $75M
31 AugEli Lilly → Merida BiosciencesAutoimmune and allergic disease programsM&AImmunologyUp to $2.875BUndisclosed upfront + milestones
28 AugGenentech (Roche) ← DualityBioNext-generation ADCs on DUPAC payload platformLicensingOncologyChina-originOver $1.0BUpfront: $45M
26 AugSK Biopharmaceuticals ← BiohavenOpakalim (Kv7 opener) and Kv7 platform for epilepsyLicensingNeuroscienceUp to $795M + milestonesUpfront: $400M near-term cash
25 AugSentivera (Arch / PHP NewCo) ← Haisco PharmaceuticalPreclinical type 2 inflammation inhibitor (asthma, atopic dermatitis) — NewCo licenseLicensingImmunologyChina-originOver $1.5BUpfront: ~$76M cash + equity
24 AugGenentech (Roche) ← Hanmi PharmaceuticalHM17321, CRFR2-selective urocortin-2 analog for obesityLicensingObesity & metabolicUp to ~$2.3BUpfront: $190M
10 AugJazz Pharmaceuticals → Actio BiosciencesPrecision therapy for KCNT1 epilepsyM&ANeuroscienceUp to $1.32B$820M upfront + up to $500M milestones
3 AugCurium (CapVest) → Lantheus HoldingsRadiopharmaceutical imaging and therapyM&ARadiopharmaceuticalsUp to ~$8.0B$102.50/share cash + CVR up to $12; premium 29% to 30-day VWAP
3 AugPathos AI ← Alphamab OncologyJSKN016, TROP2×HER3 bispecific ADCLicensingOncologyChina-originUp to ~$2.2BUpfront: $125M
27 Julargenx → Forte BiosciencesFB102, anti-CD122 antibody for vitiligoM&AImmunology~$2.2B$77/share cash
16 JulEli Lilly → AtaiBeckleyBPL-003 and VLS-01 for treatment-resistant depressionM&ANeuroscienceUp to ~$3.8B$6.75/share cash + CVR up to $2.50
15 JulAvere Therapeutics ← Hansoh PharmaHS-20118 (AVR-001), oral IL-23R antagonistLicensingImmunologyChina-originUp to ~$2.3BUpfront: $120M
14 JulAstraZeneca ← Dizal PharmaceuticalZegfrovy (sunvozertinib), EGFR exon 20 NSCLC — global rightsLicensingOncologyChina-originUp to $1.5BUpfront: $600M
14 JulSpero Therapeutics ← Innovent BiologicsIBI355 / SP001, Fc-silent anti-CD40L antibodyLicensingImmunologyChina-originUp to ~$1.1BUpfront: Undisclosed
8 JulAstraZeneca ← Sino Biopharm (CTTQ)TQC3721, inhaled PDE3/4 inhibitor for COPDLicensingRespiratoryChina-originUp to ~$2.1BUpfront: $200M
6 JulVertex → Crinetics PharmaceuticalsPalsonify for acromegaly; atumelnantM&ARare disease~$10.0B$85/share cash; premium 127% to 30-day VWAP
6 JulNovartis → Myricx BioNMT-inhibitor payload ADCsM&AOncologyUp to $1.5B$1.1B upfront + up to $400M milestones
2 JulAstraZeneca ← CSPC PharmaceuticalTwo preclinical siRNA candidates for kidney diseaseLicensingCardiovascular & renalChina-originUp to $1.77BUpfront: $30M
30 JunBoulevard Bio ← METiS TechBioMTS-128, trispecific T-cell engager — NewCo licenseLicensingImmunologyChina-originUp to ~$1.62BUpfront: $20M
29 JunIpsen → Kartos TherapeuticsNavtemadlin for myelofibrosisM&AOncologyUp to $1.75B$450M upfront + up to $1.3B milestones
24 JunEli Lilly ← Abbisko TherapeuticsDiscovery collaboration on Lilly-selected targetsLicensingPlatform / multi-areaChina-originUp to ~$1.9BUpfront: Undisclosed
24 JunNovartis ← Antares TherapeuticsSmall-molecule discovery against oncology targetsLicensingOncologyUp to ~$1.9BUpfront: $105M
22 JunAbbVie → Apogee TherapeuticsLong-acting IL-13 antibody for atopic dermatitisM&AImmunology~$10.9B$135.11/share cash
22 JunNuvectis Pharma ← Haisco PharmaceuticalNXP100 (oral factor B inhibitor) and NXP200 (BRAF inhibitor) — ex-China rightsLicensingImmunologyChina-originUp to ~$1.46BUpfront: Up to $40M upfront & near-term
21 JunSK Biopharmaceuticals ← Insilico MedicineAI-designed candidates for neuroimmune CNS diseaseLicensingNeuroscienceChina-originOver $2.5BUpfront: Up to $18M upfront & near-term
17 JunBiogen → RayTheraInflammatory disease programM&AImmunologyUp to $1.0BUndisclosed upfront + milestones
10 JunNovartis ← Orionis BiosciencesMolecular glue discovery platformLicensingPlatform / multi-areaUp to ~$1.4BUpfront: $40M
9 JunGSK → NuvalentROS1 and ALK inhibitors for lung cancerM&AOncology~$10.6B$124/share cash
9 JunEli Lilly ← AlzeCure PharmaACD680 (Alzstatin) for Alzheimer’s diseaseLicensingNeuroscienceOver $1.0BUpfront: $10M
8 JunRoche ← Nurix TherapeuticsBexobrutideg (BTK degrader) — co-developmentLicensingOncologyUp to $2.3BUpfront: $700M
8 JunIncyte → Vega TherapeuticsPhase 3 bleeding-disorder assetM&ARare diseaseUp to $2.0B$1.25B upfront + up to $750M sales milestones
8 JunJohnson & Johnson → Firefly BioDegrader-antibody conjugate platformM&AOncology$1.0BAll cash
3 JunAlnylam ← InceptiveAI-designed siRNA therapeuticsLicensingPlatform / multi-areaUp to $2.0BUpfront: $30M (cash + equity)
3 JunEli Lilly ← Ascidian TherapeuticsRNA exon editing for inherited kidney diseaseLicensingCardiovascular & renalUp to $1.9BUpfront: Undisclosed
2 JunTravere Therapeutics ← Everest MedicinesCivorebrutinib (BTK inhibitor) for rare kidney diseaseLicensingCardiovascular & renalChina-originUp to ~$1.14BUpfront: $112.5M
1 JunEli Lilly ← Haisco PharmaceuticalDiscovery collaboration across multiple areasLicensingPlatform / multi-areaChina-originUp to ~$3.05BUpfront: Up to $87M upfront & near-term
1 JunServier → Edgewise Therapeutics (muscular dystrophy business)Sevasemten for muscular dystrophiesM&ARare diseaseUp to $2.65B$1.55B upfront + up to $1.1B milestones
1 JunEli Lilly ← Hanmi PharmaceuticalSonefpeglutide (LAPS GLP-2 analog) for short bowel syndromeLicensingGastrointestinalUp to ~$1.26BUpfront: $75M
28 MayPfizer ← Innovent Biologics12 early-stage ADC and multispecific oncology programsLicensingOncologyChina-originUp to $10.5BUpfront: $650M
26 MayEli Lilly → Vaccine CompanyEpstein-Barr virus vaccineM&AInfectious diseaseUp to $1.55BUndisclosed upfront + milestones
26 MayEli Lilly → CurevoShingles vaccineM&AInfectious diseaseUp to $1.5BUndisclosed upfront + one milestone
22 MayCVC / GBL consortium → RecordatiSpecialty and rare disease pharma (take-private)M&ASpecialty & generics~€10.7B€51.29/share tender offer (reported raised to €53)
18 MayRegeneron ← Parabilis MedicinesAntibody–Helicon peptide conjugates, five targetsLicensingPlatform / multi-areaUp to ~$2.3BUpfront: $50M + $75M equity
12 MayBristol Myers Squibb ← Jiangsu Hengrui13 oncology, hematology and immunology programsLicensingOncologyChina-originUp to ~$15.2BUpfront: $600M (+$350M anniversary payments)
7 MayAngelini Pharma → Catalyst PharmaceuticalsRare neuromuscular franchiseM&ARare disease~$4.1B$31.50/share cash; premium 28% to 30-day VWAP
6 MayBayer → Perfuse TherapeuticsRetinal disease programM&AOphthalmologyUp to $2.45B$300M upfront + milestones
6 MayGSK ← SiranBioSA030, siRNA for cardiometabolic diseaseLicensingObesity & metabolicChina-originUp to ~$1.0BUpfront: Undisclosed
5 MayMadrigal ← Arrowhead PharmaceuticalsARO-PNPLA3, siRNA for MASHLicensingObesity & metabolicUp to $1.0BUpfront: $25M
3 MayUCB → Candid TherapeuticsT-cell engagers for autoimmune diseaseM&AImmunologyUp to $2.2B$2.0B upfront + up to $200M milestones
1 MayARCHIMED → Esperion TherapeuticsBempedoic acid cholesterol franchiseM&ACardiovascular & renalUp to ~$1.1B$3.16/share cash + up to $100M CVR; premium 58% to prior close
29 AprChiesi → KalVista PharmaceuticalsHereditary angioedema franchiseM&ARare disease~$1.9B$27/share cash
27 AprEli Lilly → Ajax TherapeuticsMyeloproliferative neoplasm programM&AOncologyUp to $2.3BUndisclosed upfront + milestones
26 AprSun Pharma → OrganonWomen’s health, biosimilars and established brandsM&ASpecialty & generics~$11.75B enterprise value$14/share cash
22 AprAmneal → Kashiv BioSciencesBiosimilars platformM&ASpecialty & genericsUp to $1.1B$375M cash + $375M stock + up to $350M milestones
20 AprBiogen ← TJ BiopharmaFelzartamab — Greater China rightsLicensingImmunologyChina-originUp to $850MUpfront: $100M
19 AprEli Lilly → Kelonia TherapeuticsIn vivo CAR-T for cancerM&AOncologyUp to $7.0B$3.25B upfront + milestones
17 AprUCB → Neurona TherapeuticsRegenerative cell therapy for epilepsyM&ANeuroscienceUp to $1.15B$650M upfront + up to $500M milestones
7 AprGilead → TubulisTUB-040 ADC and conjugation platformM&AOncologyUp to $5.0B$3.15B upfront + up to $1.85B milestones
6 AprNeurocrine Biosciences → Soleno TherapeuticsVykat XR for Prader-Willi syndromeM&ARare disease~$2.9B$53/share cash; premium 51% to 30-day VWAP
31 MarEli Lilly → Centessa PharmaceuticalsOrexin agonists for sleep disordersM&ANeuroscienceUp to ~$7.8B$38/share cash + CVR up to $9
31 MarBiogen → Apellis PharmaceuticalsEmpaveli and Syfovre (complement C3)M&ARare disease~$5.6B + CVR$41/share cash + Syfovre sales CVR; premium 86% to 90-day VWAP
29 MarEli Lilly ← Insilico MedicinePreclinical oral candidates from AI platformLicensingPlatform / multi-areaChina-originUp to ~$2.75BUpfront: $115M
27 MarNovartis → ExcellergyNext-generation anti-IgE for allergyM&AImmunologyUp to $2.0BUpfront + milestones
27 MarOtsuka → Transcend TherapeuticsNeuropsychiatry pipelineM&ANeuroscienceUp to ~$1.23B$700M upfront + up to $525M milestones
25 MarMerck & Co. → Terns PharmaceuticalsTERN-701 for chronic myeloid leukemiaM&AOncology~$6.7B$53/share cash; premium 31% to 60-day VWAP
23 MarGilead (with Galapagos) → Ouro MedicinesT-cell engager for autoimmune diseaseM&AImmunologyUp to ~$2.18B$1.675B upfront + up to $500M milestones
23 MarSanofi ← Kali TherapeuticsKT501, trispecific T-cell engager for autoimmune diseaseLicensingImmunologyUp to ~$1.23BUpfront: $180M upfront & near-term
6 MarServier → Day One BiopharmaceuticalsPediatric low-grade glioma franchiseM&AOncology~$2.5B$21.50/share cash
4 MarSanofi ← Sino Biopharm (CTTQ)Rovadicitinib (approved in China for myelofibrosis)LicensingOncologyChina-originUp to $1.53BUpfront: $135M
3 MarUCB ← AntengeneATG-201, CD19×CD3 T-cell engager for autoimmune diseaseLicensingImmunologyChina-originOver $1.18BUpfront: $80M upfront & near-term
24 FebSolstice Oncology (NewCo) ← Harbour BioMedPorustobart (HBM4003), anti-CTLA-4 antibody — NewCo licenceLicensingOncologyChina-originUp to ~$1.2BUpfront: $55M cash + >$50M equity
24 FebGSK ← Frontier BiotechnologiesTwo siRNA candidatesLicensingPlatform / multi-areaChina-originUp to ~$1.0BUpfront: $40M
23 FebGilead → ArcellxAnito-cel, BCMA CAR-T for multiple myelomaM&AOncology~$7.8B$115/share cash + $5 CVR; premium 68% to 30-day VWAP
23 FebAstellas ← Vir BiotechnologyVIR-5500, PSMA dual-masked T-cell engagerLicensingOncologyUp to ~$1.7BUpfront: $335M (cash, equity & near-term)
18 FebNovartis ← Unnatural ProductsMacrocyclic peptides for cardiovascular targetsLicensingCardiovascular & renalUp to $1.8BUpfront: $100M
17 FebEli Lilly ← CSLClazakizumab (anti-IL-6)LicensingImmunologyUndisclosed milestones + royaltiesUpfront: $100M
13 FebGilead ← Genhouse BioGH31, MAT2A inhibitor for MTAP-deleted cancersLicensingOncologyChina-originUp to ~$1.53BUpfront: $80M
11 FebMadrigal ← Ribo Life ScienceSix preclinical siRNA programs for MASHLicensingObesity & metabolicChina-originUp to ~$4.4BUpfront: $60M
9 FebEli Lilly → Orna TherapeuticsIn vivo CAR-T for autoimmune diseaseM&AImmunologyUp to $2.4BUndisclosed upfront + milestones
9 FebTakeda ← IambicAI-designed small-molecule programs + NeuralPLexer accessLicensingPlatform / multi-areaOver $1.7BUpfront: Undisclosed
8 FebEli Lilly ← Innovent BiologicsOncology and immunology programsLicensingOncologyChina-originUp to ~$8.85BUpfront: $350M
2 FebGenentech (Roche) ← SanegeneBioRNAi program (undisclosed target)LicensingPlatform / multi-areaUp to $1.7BUpfront: $200M
30 JanAstraZeneca ← CSPC PharmaceuticalEight obesity and type 2 diabetes programs incl. SYH2082 (GLP-1R/GIPR)LicensingObesity & metabolicChina-originUp to $18.5BUpfront: $1.2B
29 JanEli Lilly ← Repertoire Immune MedicinesTolerizing therapies for autoimmune diseaseLicensingImmunologyUp to ~$1.9BUpfront: $85M
28 JanEli Lilly ← Seamless TherapeuticsRecombinase genetic medicines for hearing lossLicensingGenetic medicineOver $1.12BUpfront: Undisclosed (+ R&D funding)
20 JanGSK → RAPT TherapeuticsLong-acting anti-IgE antibody for food allergyM&AImmunology~$2.2B ($1.9B net of cash)All cash
12 JanAbbVie ← RemeGenRC148, PD-1/VEGF bispecific antibodyLicensingOncologyChina-originUp to $5.6BUpfront: $650M
12 JanNovartis ← SciNeuroAmyloid-β antibody with blood-brain-barrier shuttleLicensingNeuroscienceChina-originUp to ~$1.7BUpfront: $165M
9 JanRoche ← MediLink TherapeuticsYL201 (tambotatug pelitecan), B7-H3 ADC — ex-China rightsLicensingOncologyChina-originUndisclosed milestones + royaltiesUpfront: $570M upfront & near-term
7 JanEli Lilly → Ventyx BiosciencesOral therapies for inflammatory diseasesM&AImmunology~$1.2BAll cash; premium 62% to 30-day VWAP
6 JanEli Lilly ← Nimbus TherapeuticsOral obesity programLicensingObesity & metabolicUp to ~$1.3BUpfront: $55M upfront & near-term
5 JanSanofi ← Earendil LabsBispecific antibodies for autoimmune diseaseLicensingImmunologyUp to $2.56BUpfront: Up to $160M upfront & near-term
2 JanAbbVie ← ZelgenAlveltamig (ZG006), DLL3 trispecific T-cell engager — option to licenseLicensingOncologyChina-originUp to ~$1.2BUpfront: $100M (+$60M near-term)

Licensing: buyer ← licensor. M&A: acquirer → target. The licensor or target name links to the deal’s source.

For analysis of each market, see our biotech licensing deal tracker, pharma M&A tracker and China outbound licensing tracker.

2026 Pharma Deals by Month

The number of deals in the database announced each month, and the largest deal of the month by headline value. Use the month filter above to see every deal for a given month.

MonthLicensingM&ALargest deal
January 202692AstraZeneca ← CSPC Pharmaceutical (Up to $18.5B)
February 2026102Eli Lilly ← Innovent Biologics (Up to ~$8.85B)
March 202647Eli Lilly → Centessa Pharmaceuticals (Up to ~$7.8B)
April 202618Sun Pharma → Organon (~$11.75B enterprise value)
May 202657Bristol Myers Squibb ← Jiangsu Hengrui (Up to ~$15.2B)
June 2026137AbbVie → Apogee Therapeutics (~$10.9B)
July 202654Vertex → Crinetics Pharmaceuticals (~$10.0B)
August 202653Curium (CapVest) → Lantheus Holdings (Up to ~$8.0B)
September 2026121Eli Lilly ← InnoCare Pharma (Up to ~$3.35B)
October 202683Roche ← Hansoh Pharma (Over $15B)

October covers deals announced up to 19 October. Headline values include contingent payments where disclosed.

Largest Deals of 2026 So Far

Acquisitions

  1. CVC / GBL consortium → Recordati — ~€10.7B, 22 May
  2. Sun Pharma → Organon — ~$11.75B enterprise value, 26 April
  3. AbbVie → Apogee Therapeutics — ~$10.9B, 22 June
  4. GSK → Nuvalent — ~$10.6B, 9 June
  5. Vertex → Crinetics Pharmaceuticals — ~$10.0B, 6 July

Licensing deals

  1. AstraZeneca ← CSPC Pharmaceutical — Up to $18.5B, 30 January
  2. Bristol Myers Squibb ← Jiangsu Hengrui — Up to ~$15.2B, 12 May
  3. Roche ← Hansoh Pharma — Over $15B, 19 October
  4. Pfizer ← Innovent Biologics — Up to $10.5B, 28 May
  5. Eli Lilly ← Innovent Biologics — Up to ~$8.85B, 8 February

Licensing headline values add up milestones that are paid only if the program succeeds; upfront cash is typically a small fraction. Acquisition values are the announced price, with contingent value rights included where the value reads “up to”. Euro-denominated deals are ranked at an approximate dollar conversion.

Most Active Dealmakers

Companies with three or more deals in the database, counting licensing deals and acquisitions together. Genentech deals are counted with Roche.

CompanyLicensingAcquisitionsTotal
Eli Lilly12921
Roche12012
Novartis628
AstraZeneca505
Gilead235
GSK325
Sanofi404
AbbVie213
Biogen123
UCB123

Reading the buyer table

Several of the most active buyers use both routes, licensing early programs and acquiring companies outright. For a biotech screening potential partners, a buyer’s recent deal mix — which areas it is active in, and whether it licenses or acquires — is a useful first filter.

The 2026 Deal Market in Context

The database lists the largest deals; market totals count every deal. J.P. Morgan’s quarterly Biopharma Licensing and Venture Report, based on DealForma data, gives the overall picture:

MeasureJan–Sep 2026Full year 2025
Biopharma M&A, upfront value$138.9B$122.1B
Biopharma M&A, deals113—
R&D licensing, announced value$221.1B$274.3B

M&A has already passed its 2025 total, and licensing had reached 81% of its 2025 record by the end of September. The two are measured differently: M&A values count upfront cash, while licensing values include milestones, of which only about 6% was paid upfront in 2026. China is the biggest single source of licensed assets — China-origin assets made up 51% of big pharma licensing deals with $50 million or more upfront through Q3, per J.P. Morgan. Our China licensing opportunities guide covers how those deals are structured.

Using the database for valuation comparables? Pair it with our rNPV valuation guide and term sheet guide.

Frequently Asked Questions

What is in the Vision Lifesciences pharma deals database?

116 biopharma deals announced in 2026 and verified against their sources: 72 licensing, collaboration and option deals with a disclosed total of $1 billion or more or an upfront of $100 million or more, and 44 acquisitions of drug companies or drug businesses worth $1 billion or more. Each entry shows the parties, asset, therapeutic area, terms and a link to the source.

Can I download the pharma deals data?

Yes. The Download CSV button exports the deals currently shown in the table, after any filters, with type, date, parties, asset, area, values, terms and source links. If you use the data, please cite Vision Lifesciences as the source.

What were the biggest pharma deals of 2026?

By headline value, the largest acquisitions in the database are CVC / GBL consortium–Recordati (~€10.7B), Sun Pharma–Organon (~$11.75B enterprise value) and AbbVie–Apogee Therapeutics (~$10.9B). The largest licensing deals are AstraZeneca–CSPC Pharmaceutical (up to $18.5B), Bristol Myers Squibb–Jiangsu Hengrui (up to ~$15.2B) and Roche–Hansoh Pharma (over $15B); licensing values include milestones that may never be paid.

How much pharma M&A and licensing was announced in 2026?

From January to September 2026, biopharma M&A totaled $138.9 billion of upfront value across 113 deals, already above the $122.1 billion of 2025, and announced R&D licensing value reached $221.1 billion, against $274.3 billion for all of 2025, according to J.P. Morgan’s Q3 2026 Biopharma Licensing and Venture Report (DealForma data).

Which companies made the most pharma deals in 2026?

Eli Lilly leads the database with 12 licensing deals and 9 acquisitions, followed by Roche with 12 and Novartis with 8.

How does this database relate to market-wide deal totals?

Market totals, such as J.P. Morgan’s quarterly figures based on DealForma data, count every announced deal, including smaller deals and those with undisclosed terms. This database complements them at deal level: it lists the year’s major deals with publicly disclosed terms, each checked against its source, and is free to search and download.

Methodology & Sources

Licensing deals are licensing, collaboration and option agreements announced in 2026 with a disclosed total of $1 billion or more or an upfront of $100 million or more; M&A and royalty sales are excluded. Acquisitions are purchases of drug companies or drug businesses announced in 2026 with a headline value of $1 billion or more; tools, diagnostics, CDMO and services deals are excluded. Dates are announcement dates. Terms are as disclosed, and “up to” values include contingent payments. “China-origin” marks licensors domiciled in mainland China or Hong Kong. Euro-denominated deals keep their euro values; for sorting by size they are converted at an approximate rate. Each deal links to the source it was checked against.

Sources:

  1. Vision Lifesciences research: our own deal tracking and insights from our day-to-day cross-border licensing and M&A advisory work (about us)
  2. Company announcements and primary reports for each deal, linked in the database
  3. J.P. Morgan, Q3 2026 Biopharma Licensing and Venture Report (DealForma data through 30 September 2026)

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